PROVIDED ARE A METHOD OF CONVENIENTLY AND EFFICIENTLY REMOVING ABNORMAL PRION PROTEIN FROM A BLOOD PRODUCT AND A METHOD OF REMOVING LEUKOCYTE SIMULTANEOUSLY WITH ABNORMAL PRION PROTEIN. THE METHOD OF REMOVING AN ABNORMAL PRION PROTEIN FROM A BLOOD PRODUCT INCLUDES FILTERING THE BLOOD PRODUCT THROUGH A FILTER FILLED WITH A CARRIER COATED WITH A POLYMER, WHICH IS COMPOSED OF THREE UNITS INCLUDING 20 MOL% OR MORE AND 40 MOL% OR LESS OF A UNIT ORIGINATING FROM A HYDROPHOBIC POLYMERIZABLE MONOMER,5 MOL% OR MORE AND 13 MOL% OR LESS OF A UNIT ORIGINATING FROM A POLYMERIZABLE MONOMER CONTAINING A BASIC NITROGEN-CONTAINING PART, AND A UNIT ORIGINATING FROM A POLYMERIZABLE MONOMER CONTAINING A PROTONIC NEUTRAL HYDROPHILIC PART AS THE BALANCE, AND THEN RECOVERING THE FILTERED BLOOD PRODUCT. FIGURE 1.