The Government of the United States of America; as represented by the Secretary of the Navy
发明人:
André A. Adams,Kyle A. DiVito,Stella H. North,Michael A. Daniele
申请号：
US15697607
公开号：
US20180064527A1
申请日:
2017.09.07
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Synthetic human blood vessels can be constructed using human brain derived endothelial cells and incorporated into a tissue model that contains astrocytes and other neurons and microglia. Multi-cell type microvessels incorporate cell types such as astrocytes and pericytes in order to construct a highly representative blood-brain barrier in vitro model with a functional lumen containing brain-derived microvascular endothelial cells and a polymer wall containing human astrocytes and/or pericytes.
