New quinoline compounds and uses thereof

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专利权人:

シェンヤン ファーマシューティカル ユニバーシティ

发明人:

ゴーン ピン,ジャオ ヤンファーン,リウ ヤージーン,ジャイ シン

申请号：

JP2015540034

公开号：

JP6126233B2

申请日:

2013.10.24

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The invention relates to a series of quinoline derivatives of general formula I, pharmaceutically acceptable salts, hydrates, solvates or prodrugs. Thereof M, R 1 , R 2 , X, Y and n are defined as claims. And the compounds of general formula I show potent inhibitory activity gainst c-Met kinase. The present invention further relates to the uses of the compounds, pharmaceutically acceptable salts and hydrates for the preparation of medicaments for the treatment and/or prevention of diseases caused by abnormal expression of c-Met kinase, especially for treatment and/or prevention of cancer.

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中国工程科技知识中心

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