The big ring of hydrazine has the factor XI, plasma thromboplastin antecedent A of inhibitory activity

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专利权人:

브리스톨-마이어스 스큅 컴퍼니

发明人:

시, 준,유잉, 윌리엄 알.,핀토, 도널드 제이.피.

申请号：

KR1020187027820

公开号：

KR1020180117156A

申请日:

2017.03.01

申请国别(地区):

KR

年份:

2018

代理人:

摘要：

The present invention provides formula (I) compound (: or its stereoisomer, tautomer or pharmaceutically acceptable salt, wherein all variables are as defined herein. Compound is selectivity factor XIa inhibitor or the double inhibitor of FXIa and plasma kallikrein. Thromboembolic disorders and/or inflammatory conditions are treated the invention further relates to the pharmaceutical composition comprising compound and using it.

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