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Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors
专利权人:
Janssen Pharmaceutica NV
发明人:
Patrick Rene Angibaud,Laurence Anne Mevellec,Bruno Roux,Pierre-Henri Storck,Christophe Meyer,Jorge Eduardo Vialard
申请号:
US14829493
公开号:
US09598396B2
申请日:
2015.08.18
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention provides compounds of formula (I), their use as inhibitors of tubulin polymerization and their use as PARP inhibitors as well as pharmaceutical compositions comprising said compounds of formula (I)wherein R1, R2, R3, R4, R5, R6, R7 and Y have defined meanings.
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