The Regents of the University of Colorado; a body corporate
发明人:
申请号:
EP15749644.9
公开号:
EP3105328A4
申请日:
2015.02.11
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Described herein are methods and vectors for rational, multiplexed manipulation of chromosomes within open reading frames (e.g., in protein libraries) or any segment of a chromosome in a cell or population of cells, in which various CRISPR systems are used.