CHO, YONG SEO,조용서,MIN, SUN JOON,민선준,PAE, AE NIM,배애님,LEE, JAE KYUN,이재균,RHIM, HYE WHON,임혜원,CHOI, KEE HYUN,최기현,SEO, SEON HEE,서선희,SONG, CHI MAN,송치만,KU, SU JIN,구수진
申请号：
KR1020110016788
公开号：
KR1020120097288A
申请日:
2011.02.24
申请国别(地区):
KR
年份:
2012
代理人:
摘要：
PURPOSE: A pharmaceutical composition containing 1,4-diazepane pyrazole compound and a pharmaceutically acceptable salt thereof is provided to be used as an agent for preventing or treating brain diseases, heart diseases, cancer, epilepsy, and pain.CONSTITUTION: A 1,4-diazepane pyrazole compound is denoted by chemical formula 1. A pharmaceutical composition for preventing and treating brain diseases such as epilepsy, depression, Parkinsons diseases, dementia, sleep disorders, or heart diseases such as hypertension, cardiac arrhythmia, or myocardial infarction, or pain contains the compound of chemical formula 1 as an active ingredient. A method for preparing the compound of chemical formula 1 comprises a step of reacting pyrazolemethyl amine of chemical formula 2 with chloroacetyl chloride.COPYRIGHT KIPO 2013본 발명은 T-형 칼슘 채널에 대하여 약학적 활성을 보이는 1,4-다이아제판 피라졸 화합물 및 약제학적으로 허용 가능한 이의 염, 이들 화합물의 제조방법, 그리고 이들 화합물이 유효성분으로 함유된 약제조성물에 관한 것이다.
