Wolfgang Möller,Dieter Rudnick,Oliver Maneg,Michael Rodemer,Matthias Germer,Veit Braun
申请号：
US15348121
公开号：
US10059759B2
申请日:
2016.11.10
申请国别(地区):
US
年份:
2018
代理人:
摘要：
An antibody preparation suitable for intravenous administration in humans includes IgG, IgA and at least 5 % IgM antibodies by weight of the total amount of antibodies. The preparation is prepared from human plasma, has specific complement activating activity, and, in an in vitro assay with human serum suitable to determine the ability of the antibody preparation to activate complement unspecifically, the antibody preparation generates substantially no C5a and/or substantially no C3a. The antibody preparation can have medical uses.
