NOH, SANG EUN,LEE, SOON DONG,LEE, HYEON YOUL,HWANG, SEUNG TAEH,KIM, HA EUN,CHOI, MIN HO
申请号：
CA3068550
公开号：
CA3068550A1
申请日:
2018.06.29
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The present invention relates to a pharmaceutical composition for preventing or treating osteoarthritis comprising a cell or a cell group having a specific size or less, a kit for preparing a cellular therapeutic agent, and a method for preparing a therapeutic agent for osteoarthritis. Mixed cells, which are selected to be equal to or less than a specific size as an effective ingredient of the present invention, of mammalian cells transformed with TGF-ß and untransformed mammalian cells minimize aggregation between chondrocytes and have a beneficial therapeutic effect. In addition, when the mixed cells of the selected specific size or less are administered to a patient, patient compliance may be improved, and it is easy to manage quality in a therapeutic agent production facility or a hospital.
