Joel P. Schneidér,Monica C. Branco,Darrin J. Pochan,Norman J. Wagner
申请号：
US12533708
公开号：
US08834926B2
申请日:
2009.07.31
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A hydrogel for delayed release of an anionic macromolecule, wherein the hydrogel comprises the anionic macromolecule, 150 mM NaCl, and a peptide selected from the group consisting of SEQ ID NO:1 through SEQ ID NO:33 in an aqueous medium at a pH of 7.4 wherein the anionic macromolecule has an isoelectric point of at most 6.8 and wherein the hydrogel is capable of retaining at least 25% of the anionic macromolecule after 28-day extraction at 37° C. with a pH=7.4 BTP buffer containing 150 mM NaCl.
