Samuel S. Murray;Keyvan Behnam;Elsa J. Brochmann-Murray
发明人:
Samuel S. Murray,Keyvan Behnam,Elsa J. Brochmann-Murray
申请号:
US13481648
公开号:
US08759296B2
申请日:
2012.05.25
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the overall osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.