Christian Andrew Baumann,Michael David Gaul,Dana L. Johnson,Robert W. Tuman
申请号：
US12421778
公开号：
US08557847B2
申请日:
2009.04.10
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The invention is directed to a method of inhibiting FLT3 tyrosine kinase activity or expression or reducing FLT3 kinase activity or expression in a cell or a subject comprising the administration of a farnesyl transferase inhibitor and a FLT3 kinase inhibitor selected from compounds of Formula I′:Included within the present invention is both prophylactic and therapeutic methods for treating a subject at risk of (or susceptible to) developing a cell proliferative disorder or a disorder related to FLT3.
