Elizabeth Punnoose;Michelle Nannini;Jeffrey Wallin;Premal Patel;Kui Lin;Deepak Sampath
发明人:
Kui Lin,Michelle Nannini,Elizabeth Punnoose,Deepak Sampath,Jeffrey Wallin,Premal Patel
申请号：
US14009314
公开号：
US20150064171A1
申请日:
2012.03.30
申请国别(地区):
US
年份:
2015
代理人:
摘要：
The invention provides combinations comprising a) compound of formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R5, R10, and A have any of the values defined in the specification； and b) one or more agents selected from 5-FU, a platinum agent, leucovorin, irinotecan, docetaxel, doxorubicin, gemcitabine, SN-38, capecitabine, temozolomide, paclitaxel, bevacizumab, pertuzumab, tamoxifen, rapamycin and lapatinib. The combinations are particularly useful for treating hyperproliferative disorders, such as cancer.
