PROBLEM TO BE SOLVED: To solve the problems such as a difficulty in accurately removing a surface reflection component of a highlight part and the like, a high calculation cost, and a disadvantage in reducing a diameter of the tip of an electronic scope.SOLUTION: An image signal generating device includes: means for extracting a first color signal corresponding to a first wavelength region and a second color signal corresponding to a second wavelength region from image signals of a biological tissue irradiated with the irradiation light having a plurality of wavelength regions including first and second wavelength regions whose absorption properties in the biological tissue are different means for calculating a pixel value approximate distribution approximate to the pixel value distribution of the second color signal based on the pixel value distribution of the first color signal means for generating an image signal of a surface reflection component of the biological tissue based on a difference between the pixel value approximate distribution of the second color signal and the pixel value distribution of the second color signal and means for generating an image signal of an internal reflection component of the biological tissue by subtracting the image signal of the surface reflection component from the image signal of the biological tissue.SELECTED DRAWING: Figure 4COPYRIGHT: (C)2016,JPO&INPIT【課題】ハイライト部分等の表面反射成分を精度良く除去することが難しく、また、演算コストが高かったり電子スコープ先端の細径化に不利であったりする等の問題がある。【解決手段】画像信号生成装置を、生体組織の特定の内部構造を強調するための特定波長にピーク強度を持つ狭帯域光及び狭帯域光以外の少なくとも一部の帯域の光を含む照射光により照射された生体組織であって、所定の撮像装置により撮像された生体組織の画像信号の中から特定波長に対応する色信号を抽出する手段と、抽出された色信号に基づいて生体組織の表面反射成分の画像信号を生成する手段と、生体組織の画像信号から表面反射成分の画像信号を減算することにより、生体組織の内部反射成分の画像信号を生成する手段より構成する。【選択図】図4
