Problem to be solved: to provide an activator for activation of the biodefense gene by the keap1-nrf2 system which can be used as a food and drink, and can be used as a food and drink product, and has an excellent activation activity of the biodefense gene by the keap1-nrf2 system.A method for activating living defense genes by keap1-nrf2 system containing barley young leaves or their processed products containing specific components, and food products containing the activating agents.Because the activating agent and the food and drink have the activation action of the bioprotective gene by the keap1-nrf2 system, the effect of prevention and the improvement of the antioxidative activity and the detoxification ability of the organism, and the prevention and the improvement (various) of various diseases which the oxidative stress is concerned, and the keap1-nrf2 system are Prevention or improvement of disease or condition (symptom) caused by the activity lowering of the biodefense gene expression is expected.No selection【課題】長期間服用しても安全であり、飲食品として使用でき、Ｋｅａｐ１－Ｎｒｆ２システムによる生体防御遺伝子の優れた活性化作用をもつＫｅａｐ１－Ｎｒｆ２システムによる生体防御遺伝子の活性化用剤を提供する。【解決手段】特定の成分を含む大麦若葉又はその処理物を有効成分として含むＫｅａｐ１－Ｎｒｆ２システムによる生体防御遺伝子の活性化用剤、該活性化用剤を含んでなる飲食品。かかる活性化用剤や飲食品は、Ｋｅａｐ１－Ｎｒｆ２システムによる生体防御遺伝子の活性化作用を有するので、生体の抗酸化防御や解毒能力を高め、酸化ストレスが関与する諸種の疾患の予防又は改善（治療）等の効果、Ｋｅａｐ１－Ｎｒｆ２システムによる生体防御遺伝子発現の活性低下に起因する疾患若しくは状態（症状）の予防又は改善（治療）が期待される。【選択図】なし
