The present invention relates to bicyclo-substituted pyrazolon azo derivatives pharmaceutical acceptable salts of formula (I), methods for their preparation, pharmaceutical compositions containing the same and their use as a therapeutic agent, especially as thrombopoietin (TPO) mimetics and their use as agonists of thrombopoietin receptor. The definition of substituents in formula (I) are the same as the description.通式(I)所示的雙環取代吡唑酮偶氮類衍生物藥學上可接受的鹽、其製備方法以及含有該藥學上可接受鹽的藥物組合物、以及其作為治療劑特別是作為血小板生成素(TPO)模擬物和血小板生成素受體激動劑的用途。通式(I)中的各取代基的定義與說明書中的定義相同。
