FÜR ASCT2 SPEZIFISCHE BINDEMOLEKÜLE UND VERWENDUNGEN DAVON

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专利权人:

LLC;Medimmune

发明人:

PORE, Nabendu,BORROK III, Martin, J.,CHOWDHURY, Partha, S.,MICHELOTTI, Emil, F.,TICE, David, A.,HOLLINGSWORTH, Robert, E.,CHANG, Chien-Ying,HURT, Elaine, M.,YAO, Nai, Shun

申请号：

EP17868894

公开号：

EP3538150A4

申请日:

2017.11.08

申请国别(地区):

EP

年份:

2020

代理人:

摘要：

This disclosure provides ASCT2-binding molecules, e.g., anti-ASCT2 antibodies, and antigen-binding fragments thereof, used in methods related to cancer stem cells, e.g., binding to a cancer stem cell. In certain aspects, the ASCT2-binding molecules are conjugated to cytotoxic drugs, e.g., ASCT2 antibody-drug conjugates. In certain aspects, the ASCT2-binding molecules bind specifically to cancer stem cells expressing ASCT2.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/