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ФАКТОР II И ФИБРИНОГЕН ДЛЯ ЛЕЧЕНИЯ ГЕМОСТАТИЧЕСКИХ НАРУШЕНИЙ
专利权人:
МЕДИММЬЮН ЛИМИТЕД (GB)
发明人:
ЛОВГРЕН Анн (SE),ХАНССОН Кенни (SE)
申请号:
RU2013120033/15
公开号:
RU2013120033A
申请日:
2011.09.19
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A method for normalizing the impaired hemostasis in a mammal in need thereof, comprising administering treat clotting factor selected from the group consisting of (1) FII, (2) a combination of FII, FVIIa and FX, (3) a combination of fibrinogen and FII, FVIIa and FX and (4) and fibrinogen FII.2. A method for increasing the maximum density of a thrombus (MCF) in a mammal with impaired hemostasis comprising applying treating clotting factor selected from the group consisting of (1) FII, (2) FII combination, FVIIa and FX, (3) fibrinogen and combinations FII, FVIIa and FX, as well as (4) and fibrinogen FII.3. A method for reducing clotting time (CT) in a mammal with impaired hemostasis comprising applying treating clotting factor selected from the group consisting of (1) FII, (2) a combination of FII, FVIIa and FX, (3) fibrinogen and combinations FII, FVIIa and FX, and (4) and fibrinogen FII.4. A method of improving formation of thrombin in a mammal with impaired hemostasis comprising applying treating clotting factor selected from the group consisting of (1) FII, (2) a combination of FII, FVIIa and FX, (3) fibrinogen and combinations FII, FVIIa and FX, and and (4) and fibrinogen FII.5. A method according to any one of claims. 1-4, wherein said hemostatic disorders associated with bleeding accompanied disorder, hemorrhage, massive blood loss or traumatic event krovotecheniya.6. The method of claim. 5, wherein said massive blood loss associated with koagulopatiey.7. The method of claim. 5, wherein said bleeding disorder is accompanied by a gemofiliyu.8. The method of claim. 5, wherein said case of traumatic hemorrhage or bleeding associated with perioperative bleeding, postoperative or postpartum bleeding the blood flow1. Способ нормализации нарушенного гемостаза у нуждающегося в этом млекопитающего, включающий применение лечения фактором свертывания, выбранным из группы, состоящей из (1) FII, (2) комбинации FII, FVIIa и FX, (3) фибриногена и комбинации FII, FVIIa и FX
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