A system and method for detecting a stroke includes a non-contact ocular pulse measurement device configured to output a first and a second ocular pulse measurement signals for each of a patient's eyes, respectively. A computing system has a processor and a memory, and the memory stores instructions that when executed cause the processor to analyze the first and second ocular pulse measurements. An index of difference between the first and second ocular pulse measurements is determined, and a user interface is generated that includes a stroke advisory to the patient based on the index of difference.