PROCEDES DE PRODUCTION DE FIBRES DE COLLAGENE POLYMERISEES PAR NDGA A RESISTANCE ELEVEE, ET PROCEDES ASSOCIES DE PREPARATION DE MATERIAU PREPARATOIRE POUR COLLAGENE, APPAREILS MEDICAUX ET CONSTRUCTIONS
KOOB, THOMAS J.,PRINGLE, DOUGLAS,HERNANDEZ, DANIEL
申请号：
CA2674453
公开号：
CA2674453C
申请日:
2007.12.27
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A method of manufacturing nordihydroguaiaretic acid (NDGA) polymerizedcollagenfibers comprises: (a) treating collagen with a solution comprising NDGA； (b)drying theNDGA-treated collagen while holding the treated collagen in tension for aperiod of time； (c)washing the dried NDGA-treated collagen in a solution to remove unreactedsoluble NDGAcross-linking intermediates； (d) drying the NDGA-treated collagen whileholding the treatedcollagen in tension for a period of time； and repeating steps (a)-(d) at leastonce to producehigh-strength NDGA polymerized collagen fibers.
