PROBLEM TO BE SOLVED: To provide a novel serotonin reuptake inhibitor that combines a 5- HT2C antagonism having antidepressant activity and anxiolytic effect, and especially a 5-HT2C reverse action.SOLUTION: A compound shown by formula (1) and a salt that is allowed in pharmacology are disclosed. In the formula, R1, R2, R3 and R4 each independently denote a C1-6 alkyl group or the like R5 may denote a C4-7 alkyl group or -(CR8R9)r-E or the like.COPYRIGHT: (C)2014,JPO&INPIT【課題】抗うつ作用および抗不安作用を有する5-HT2C拮抗作用、特に5-HT2C逆作動作用を併せ持つ新しいセロトニン再取り込み阻害剤の提供。【解決手段】下記式(1)で表される化合物またはその薬学上許容される塩。[式中、R1、R2、R3およびR4は互いに独立してC1-6アルキル基等であり、R5はC4-7アルキル基または-(CR8R9)r-Eなどでありる。]【選択図】なし
