An interface for receiving electrical signals representative of a condition of a patient and for conveying representations of the electrical signals to a processing system. The interface includes at least one amplifier circuit configured to alter an amplitude of the electrical signal, a common-mode cancellation amplifier circuit coupled to the at least one amplifier circuit and configured to reduce common-mode signal noise in the electrical signals, and a bootstrap circuit coupled to the at least one amplifier circuit and configured to increase an effective input impedance at an input of the at least one amplifier circuit.
