The invention relates to the use of Kv1.5 inhibitors for producing a medicament for the therapy or prophylaxis of respiratory disorders, sleep-related respiratory disorders, central and obstructive sleep apneas, upper airway reisistance syndrome, Cheyne-Stokes respiration, snoring, disrupted central respiratory drive, sudden child death, postoperative hypoxia and apnea, muscle-related respiratory disorders, respiratory disorders after long-term ventilation, respiratory disorders during adaptation in high mountains, acute and chronic lung disorders with hypoxia and hypercapnia, neurodegenerative disorders, dementia, Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, cancer disorders, breast cancer, lung cancer, colon cancer and prostate cancer.本發明係有關使用Kv1.5抑制劑製造藥劑以治療或預防呼吸系統失調症、睡眠相關性呼吸系統失調症、中樞性與阻塞性睡眠呼吸中止症、上呼吸道阻塞症候群、陳施氏呼吸、打鼾、被中斷之中樞呼吸驅動力、幼兒猝死症、手術後組織缺氧與呼吸中止、肌肉相關性呼吸系統失調症、長期換氣後之呼吸系統失調症、高山適應期間之呼吸系統失調症、帶有組織缺氧與血碳酸過多之急性及慢性肺疾、神經退化性疾病、癡呆症、老年癡呆症、帕金森氏症、杭丁頓氏症、癌症、乳癌、肺癌、結腸癌與前列腺癌之用途。