AHMAD NADIA,BOYALL DEAN,CHARRIER JEAN DAMIEN,DAVIS CHRIS,DAVIS REBECCA,DURRANT STEVEN,ETXEBARRIA I JARDI GORKA,FRAYSSE DAMIEN,JIMENEZ JUAN MIGUEL,KAY DAVID,KNEGTEL RONALD,MIDDLETON Donald,ODONNELL MIC
申请号：
IN1907/KOLNP/2015
公开号：
IN2015KN01907A
申请日:
2015.06.17
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The present invention relates to compounds useful as inhibitors of ATR protein kinase. The invention also relates to pharmaceutically acceptable compositions comprising the compounds of this invention； methods of treating of various diseases, disorders, and conditions using the compounds of this invention； processes for preparing the compounds of this invention； intermediates for the preparation of the compounds of this invention； and methods of using the compounds in in vitro applications, such as the study of kinases in biological and pathological phenomena； the study of intracellular signal transduction pathways mediated by such kinases； and the comparative evaluation of new kinase inhibitors. The compounds of this invention have formula (I) or a pharmaceutically acceptable salt, wherein the variables are as devined herein. Moreover, The compounds of this invention have formula (I-A) or a pharmaceutically acceptable salt, wherein the variables are as defined herein.
