A COMPOSITION COMPRISING (-)-TRANS-3-(5,6-DIHYDRO-4H-PYRROLO [3,2,1-IJ] QUINOLIN-1-YL)-4-(1H-INDOL-3-YL) PYRROLIDINE-2, 5-DIONE IN COMBINATION WITH A SECOND ANTI-PROLIFERATIVE AGENT
CHAN, THOMAS C. K.,FRANCE, DENNIS S.,ISHII, KENICHI,PUCCI, PAOLO
申请号:
CA2752232
公开号:
CA2752232C
申请日:
2010.02.11
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention providesmethods of treating a cell proliferative disorder,such as a cancer, by administering to a subject inneed thereof a therapeutically effective amount ofa pyrroloquinolinyl-pyrrole-2,5-dione compoundor a pyrroloquinolinyl-pyrrolidine-2,5-dione compoundin combination with a therapeutically effectiveamount of a second anti-proliferative agent.