Extracellular Redox Enzyme System to Alleviate Disease

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专利权人:

The General Hospital Corporation

发明人:

Vamsi K. Mootha,Xiaoyan Robert Bao,Anupam Patgiri

申请号：

US16769319

公开号：

US20200291364A1

申请日:

2018.12.03

申请国别(地区):

US

年份:

2020

代理人:

摘要：

Compositions comprising (i) lactate oxidase (LOX) and Catalase (CAT), preferably in a 1:1 molar ratio； or (ii) a fusion polypeptide comprising both LOX and CAT, e.g., LOXCAT, and methods of use thereof for reducing blood lactate levels, increasing blood pyruvate levels, and/or decreasing blood lactate/pyruvate ratio in a subject.

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中国工程科技知识中心

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