A manufacturing method and manufacturing device for micronutrient supplement granules involve sequentially performing physically extruding, grinding and sieving of trace elements to obtain micronutrient supplement granules having a granule size of 35-380 μm and a granule strength greater than 10 N with a tablet press, a first grinding and granulating machine and a sieving unit including primary and secondary sieving machines. A discharge end of the tablet press is connected to a feed end of the first grinding and granulating machine, of which a discharge end is connected to a feed end of the sieving unit. Feed and discharge ends of the primary sieving machine are respectively connected to discharge end of the first grinding and granulating machine and feed end of the secondary sieving machine. The primary and secondary sieving machines have sieving meshes respectively with square and circular mesh holes.
