PROCESS FOR THE PREPARATION OF AN IS-UDMA BIOBASED MONOMER AND ITS USE IN THE DEVELOPMENT OF DENTAL FORMULATIONS BASED ON IS-UDMA AND BIS-GMA WITH ANTI-SHRINK AND LOW MICROFILTRATION PROPERTIES FOR APPLICATION IN DENTAL RESTORATIONS.
MARIA LYDIA BERLANGA DUARTE,Luis Alberto REYNA MEDINA
申请号：
MX2016017077
公开号：
MX2016017077A
申请日:
2016.12.19
申请国别(地区):
MX
年份:
2018
代理人:
摘要：
The present invention relates to the process of preparation and use of the urethane dimethyl acrylate monomer of isosorbide (Is-UDMA) in a copolymer formed by two acrylic monomers that are Is-UDMA and Bis-GMA, for obtaining properties with synergistic effect for the development of new dental formulations. The Is-UDMA monomer is prepared in situ, by two synthesis phases and characterized by FTIR spectroscopy and proton nuclear magnetic resonance (+ HRMN) techniques. The dental formulations are prepared from different concentrations were used in weight percentage of the copolymer Is-UDMA / Bis-GMA (0/100) (25/75) (50/50) (75/75) and (100/0) respectively. The efficiency of the Is-UDMA / Bis-GMA copolymer as an organic matrix in the dental formulation is evaluated by conversion of double bonds (DC) by real-time photo-polymerization kinetics (RT-FTIR) by FTIR spectroscopy, viscoelastic properties, shrinkage or contraction and microfiltration in vitro, using premolar teeth. Some combination s achieve making the use of the two acrylic monomers more efficient since they proved to increase the final properties in the evaluated dental resins. Furthermore, in vitro microfiltration tests with dental organs showed that the formulations possess high synergistic potential as dental restorative materials.La presente invención presenta el proceso de preparación y uso del monómero uretano dimetil acrilato del isosorbide (Is-UDMA) en un copolímero conformado por dos monómeros acrílicos que son Is-UDMA y Bis-GMA obteniendo propiedades con efecto sinergístico para el desarrollo de nuevas formulaciones dentales. El monómero Os-UDMA fue preparado in situ, mediante dos fases de síntesis y caracterizado por técnicas de espectroscopía FTIR y resonancia magnética nuclear de protones (+HRMN) de protones. Para preparar las formulaciones dentales se usaron diferentes concentraciones en porcentaje en peso del copolímero Is-UDMA/Bis-GMA (0/100) (25/75) (50/50) (75/75) y (100/0) respectivamente. La
