Targeting VEGF-B regulation of fatty acid transporters to modulate human diseases

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专利权人:

发明人:

申请号：

EP12178908.5

公开号：

EP2548579A1

申请日:

2007.05.17

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention provides materials and methods for modulating FATP expression and/or activity in vivo. In particular, the present invention concerns an oligonucleotide which inhibits VEGF-B expression for use in the treatment or prophylaxis of type II diabetes or metabolic syndrome wherein the oligonucleotide is selected from (a) an antisense oligonucleotide that inhibits VEGF-B transcription or translation or an expression vector which expresses such an oligonucleotide or (b) a dsRNA that affects RNA interference or expresses such a dsRNA.

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中国工程科技知识中心

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http://www.ckcest.cn/home/