A medical device includes a balloon member, a port that couples a compartment interior of the balloon member to a region exterior of the balloon member, and a tubular member that defines a lumen. A distal end of the tubular member is attached to an internal surface of the balloon member within the compartment so that a portion of the internal surface of the balloon member provides a seal at a distal end of the lumen. The tubular member passes through the port, and the proximal end of the tubular member is configured to remain exterior of the compartment. The balloon member and the tubular member comprise pores wherein the tubular member is configured to be filled by a filling material delivered into the lumen of the tubular member and the filling material includes a therapeutic substance that is configured to diffuse out of the medical device through the pores of the vessel member and the tubular member.
