A catheter for angioplasty or coronary angioplasty of a vessel or tissue is described. The catheter includes a shaft having a proximal portion and a distal portion and a balloon is carried at the distal portion of the shaft. The catheter further includes wires having a profile that surrounds the balloon. A coating is carried on at least 50% of the surface of the balloon and comprises at least one drug or drug preparation and at least one lipophilic antioxidant at a ratio of 3-100% by weight of the at least one lipophilic antioxidant in relation to 100% by weight of the drug, wherein a combination of limus drugs with butylated hydroxytoluene as the lipophilic antioxidant is excluded.
