A lice brush includes a body that supports a plurality of bristles. The body also includes a handle. One or more of the plurality of bristles is configured for use in brushing a user's hair for lice. In particular, one or more of the bristles includes recesses, grooves, indentations, notches, pits or similar inwardly-extending spaces configured to facilitate removal of lice as the bristles pass through the hair. Multiple bristles can be provided in a bristle unit and multiple bristle units can be employed in a bristle assembly of the brush.