Modulators of CRTH2, particularly antagonists of CRTH2, that are useful for treating various disorders, including asthma and respiratory disorders are disclosed. The compounds fall within a genus described by formula I.Se divulgan los moduladores de CRTH2, particularmente los antagonistas de CRTH2, que son útiles para tratar varios trastornos, incluyendo el asma y los trastornos respiratorios. Los compuestos pertenecen al género descrito por la fórmula I: (FORMULA I).