composition suitable for depleting ovarian follicles in female mammals, and methods for inducing ovarian follicle depletion in a female mammal, for reducing the reproductive capacity of a mammal, for controlling the population size of a non-human mammalian population and for preparing a composition.
Provided are compositions and methods for reducing the reproductive capacity of mammals. The compositions and methods involve the use and administration of (a) a diterpenoid epoxide comprising a triptolide skeleton and which causes ovarian follicle depletion in female mammals and (b) an organic diepoxide which causes ovarian follicle depletion in female mammals.