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IMPLANTABLE MATERIAL GRAFTED WITH A CELL ANTIPROLIFERATIVE AND/OR ANTIBACTERIAL FILM SYNTHETIZED FROM A BIFUNCTIONAL MOLECULE
专利权人:
发明人:
Guy DENIAU,Cedric ZOBRIST,Maxime OUDIN,Laurent DAVID
申请号:
US14898331
公开号:
US20160129166A1
申请日:
2014.06.13
申请国别(地区):
US
年份:
2016
代理人:
摘要:
The present invention relates to an implantable material having at least one external surface grafted with a film including carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on the external surface by radical reaction of a bifunctional adhesion primer of Formula (I) or by radical reaction of an adhesion primer and a bifunctional polymerizable monomer of Formula (II).The invention also relates to a process for directly synthesizing and grafting of a film according to the invention onto at least one external surface of an implantable material. The invention further relates to the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device. The invention also relates to compounds of Formula (I) and Formula (II).
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