NOVEL FUNCTIONALLY ENHANCED MESENCHYMAL PROGENITOR CELLS CELL THERAPEUTIC COMPOSITION FOR REVASCULARIZATION OR PREVENTING VASCULAR DAMAGE INCLUDING THE SAME AND METHOD FOR PREPARING THE SAME
CHUNG HYUNG MIN,정형민,HONG KI SUNG,홍기성,SHIN JEONG MIN,신정민
申请号:
KR1020170153113
公开号:
KR1020180063817A
申请日:
2017.11.16
申请国别(地区):
KR
年份:
2018
代理人:
摘要:
One embodiment of the present invention provides a cell therapeutic composition for revascularization or vascular damage prevention, which comprises mesenchymal progenitors as an active ingredient, wherein the mesenchymal progenitors express epidermal growth factor receptors (EGF-R) at a higher level than mesenchymal stem cells (MSC) and express cluster differentiation 95 (CD95) at a lower level than mesenchymal stem cells.본 발명의 일 실시예는 중간엽 줄기세포(MSC, Mesenchymal Stem Cell)에 비해 표피성장인자 수용체(EGF-R, Epidermal Growth Factor Receptor)를 과발현하고, 중간엽 줄기세포에 비해 CD95(Cluster Differentiation 95)를 저발현하는 간엽성 전구세포(Mesenchymal Progenitor)를 유효성분으로 포함하는, 혈관 재생용 또는 혈관 손상 방지용 세포치료제 조성물을 제공한다.