B. Therese Kinsella,Patrick Guiry,Helen Reid,Barry OConnor
申请号：
US14391856
公开号：
US09388127B2
申请日:
2013.04.17
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention generally relates to compounds that function as TP antagonists for treating thrombosis and other cardiovascular, renal, or pulmonary diseases. In some embodiments, the invention provides a compound including a substituted nitro phenoxy phenyl, a sulfonylurea, and an alkyl group. In some embodiments, the invention provides a method of treating thrombosis by administering an antithrombotic compound that preferentially binds to a thromboxane receptor, has preferential binding for either TPalpha (TPα) or TPbeta (TPβ) receptor subtype.
