Ravishanker Kovi,Jayaraman Kannapan,Vasanthakumar G Ramu,Alaparthi Lakshmi Prasad,Talluri Bhushaiah Chowdary,Gaurav Kulkarni,Saiyed Akeel Ahmed Shakeel Ahmed,Veerabhadra Rao Bobbili,N V Raghavalu Dusa
申请号：
US15228689
公开号：
US09822145B2
申请日:
2016.08.04
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Racemization-free methods are disclosed for the synthesis of carfilzomib. Novel intermediates and methods of making carfilzomib employing fragment condensation using the novel intermediates are disclosed. Amorphous carfilzomib and methods of making same are disclosed.
