Central Adelaide Local Health Network Inc.;University of South Australia
发明人:
Woodcock, Joanna,Lopez, Angel,Pitson, Stuart Maxwell,Samuel, Michael Susithiran,Coolen, Carl
申请号：
AU2015330955
公开号：
AU2015330955A1
申请日:
2015.10.08
申请国别(地区):
AU
年份:
2017
代理人:
摘要：
The present disclosure relates to modulators of 14-3-3 functionality and their use in methods and compositions for preventing and/or treating various diseases, conditions and states, such as cancer and healing of wounds. Certain embodiments of the present disclosure provide a method of preventing and/or treating a disease, condition or state in a subject associated with altered 14-3-3 protein functionality and/or which would benefit from altering 14-3-3 functionality, the method comprising administering to the subject an effective amount of an agent which inhibits dimerization of the 14-3-3 protein, thereby preventing and/or treating the disease, condition or state in the subject.
