Austin L. Gurney,Timothy Charles Hoey,Aaron Ken Sato,Alexandra Lazetic,Zhimin Ji
申请号:
US13510666
公开号:
US08945569B2
申请日:
2010.11.19
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Antibodies that specifically bind to an extracellular domain of human Jagged 1 or human Jagged2 and modulate Jagged activity, and methods of using said antibodies to inhibit tumor growth are disclosed. Also described are methods of treating cancer comprising administering a therapeutically effect amount of an anti-Jagged antibody to a patient having a tumor or cancer.