The present invention relates to a system for determining vital sign information (7) of a subject (100) and a marker (10, 10, 20, 30, 40, 60, 70, 80, 90) for use in determining vital sign information (7) of a subject (100). An embodiment of a marker comprises a marker area (11, 11, 22, 35, 36 42, 48, 65, 72, 82, 92) for emitting light towards a skin (104) of the subject (100) for determining vital sign information (7) from the reflected light, and attachment means (23, 43, 73) for attaching the marker (10, 10, 20, 30, 40, 60, 70, 80, 90) to the subject (100). An embodiment of a system further comprises a detection unit (2, 52) for detecting radiation emitted by the marker (10, 10, 20, 30, 40, 60, 70, 80, 90) towards a skin (104) of the subject (100) and reflected from the skin (104) of the subject (100), and an analysis unit (6) for determining the vital sign information (7) of the subject (100) from the detected radiation reflected from the skin (104) of the subject (100).