An actively-powered temperature data logger patch with wireless data communication includes a first substrate layer, a second substrate layer, a non- adhesive release layer, and an electronics inlay disposed between the first and second substrate layers. The electronics inlay includes a sealed, flexible battery, and a flexible circuit having a temperature sensor. An outer face of the non- adhesive release layer is has release properties. A replaceable adhesive includes a carrier substrate, a structural adhesive coated on a first face and attached to the outer face of the non-adhesive release layer, and a skin-contact approved adhesive coated on a second opposite face. In another example, an auxiliary sleeve having an exterior surface with an adhesive configured to be removably applied to a subject, may partially enclose the temperature data logger patch in an internal compartment.
