PROBLEM TO BE SOLVED: To provide compositions capable of adjusting a biological clock system, the composition not having safety problems as compared with prior arts and being capable of manufacturing and utilizing in technical scale.SOLUTION: The above object of the invention can be solved by a composition containing Kaempferia parviflora and having the expression promoting effect of clock genes such as Per2, Cry1, Bmal1, and Clock, a circadian rhythm adjustment effect, and/or a sleep improving effect.SELECTED DRAWING: Figure 1COPYRIGHT: (C)2017,JPO&INPIT【課題】本発明の目的は、従来技術に比して、安全性に問題がなく、かつ、工業的規模で製造及び利用が可能である体内時計系を調節し得る組成物を提供することにある。【解決手段】上記した本発明の目的は、黒生姜(Kaempferiaparviflora)を含有し、かつ、Per2、Cry1、Bmal1及びClockといった時計遺伝子の発現促進作用、概日リズム調整作用及び/又は睡眠改善作用を有する組成物により解決される。【選択図】図1
