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IMMUNOGLOBULIN SINGLE VARIABLE DOMAIN ANTIBODY AGAINST RSV PREFUSION F PROTEIN
专利权人:
THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN;VIB VZW;UNIVERSITEIT GENT;TRUSTEES OF DARTMOUTH COLLEGE
发明人:
Xavier SAELENS,Bert SCHEPENS,Iebe ROSSEY,Barney GRAHAM,Jason MCLELLAN,Morgan GILMAN
申请号:
US15736663
公开号:
US20180179266A1
申请日:
2016.06.20
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention relates to immunoglobulin single variable domains (ISVDs) that are directed against respiratory syncytial virus (RSV). More specifically, it relates to ISVDs that bind to the prefusion form of the fusion (F) protein of RSV. The invention relates further to the use of these ISVDs for prevention and/or treatment of RSV infections, and to pharmaceutical compositions comprising these ISVDs.
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