METHODS FOR INHIBITING PLATELET AGGREGATION USING GLP-1 RECEPTOR AGONISTS

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专利权人:

Mansoor HUSAIN

发明人:

Mansoor Husain,Alison Cameron-Vendrig,Heyu Ni

申请号：

US14440227

公开号：

US20150290294A1

申请日:

2013.11.04

申请国别(地区):

US

年份:

2015

代理人:

摘要：

Methods for inhibiting platelet aggregation using glucagon-like peptide-1 receptor (GLP-1R) agonists are disclosed. GLP-1 receptors are demonstrated to be expressed in platelets and/or megakaryocytes. Activation of GLP-1 receptors by GLP-1 agonists, such as GLP-1 and exendin-4, inhibited thrombin-induced platelet aggregation.

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中国工程科技知识中心

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http://www.ckcest.cn/home/