The present disclosure pertains to a system configured to determine one or more parameters of chest wall oscillation therapy for a subject. The system comprises a wearable garment configured to provide percussion to one or more parts of a lung of a subject. The wearable garment comprises: percussion excitation elements configured to produce the percussion; and sensors configured to generate output signals conveying information related to a response of the one or more parts of the lung to the percussion. The system comprises a control unit configured to determine frequency and energy density information for the sounds made by the one or more parts of the lungs caused by the percussion, the frequency and energy density information determined based on the output signals; and determine the one or more parameters of the chest wall oscillation therapy based on the frequency and energy density information.