COMBINAISONS DE MÉDICAMENTS CONTENANT DES INHIBITEURS PDE4 ET NSAID

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专利权人:

Boehringer Ingelheim International GmbH

发明人:

NICKOLAUS, Peter,GOEGGEL, Rolf,PETER, Daniel

申请号：

EP10704367.1

公开号：

EP2400961B1

申请日:

2010.02.18

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Drug combinations which contain a PDE4-inhibitor and a non-steroidal anti-inflammatory drug (NSAID), processes for preparing them, and their use in treating in particular respiratory complaints such as COPD, chronic sinusitis, and asthma. The PDE4 inhibitors of the drug combinations include compounds of general formula 1 wherein X is SO or SO2, but preferably SO, R3 is an optionally substituted, mono- or bicyclic, unsaturated, partly saturated or saturated heterocyclic group or an optionally substituted, mono- or bicyclic heteroaryl, and R1 and R2 have the meanings given in claim 2.

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