四氫哌喃基胺基-吡咯並嘧啶酮和使用彼之方法农业专利-农业专业知识服务系统

发明人:: LAPIERRE, JEAN-MARC,拉比尔　圣马克,拉比爾　聖馬克,EATHIRAJ, SUDHARSHAN,伊希拉杰　苏德哈山,伊希拉傑　蘇德哈山,NAMDEV, NIVEDITA,南戴夫　尼维德塔,南戴夫　尼維德塔,SCHWARTZ, BRIAN,史瓦兹　布莱恩,史瓦茲　布萊恩,OTA, YUSUKE,太田悠介,太田悠介,MOMOSE, TAKAYUKI,百濑孝幸,百瀨孝幸,TSUNEMI

摘要：: The application relates to a compound of Formula (I):or a pharmaceutically acceptable salt thereof, tautomer, prodrug, solvate, metabolite, polymorph, analog or derivative thereof, which modulates the activity of BTK, a pharmaceutical composition comprising the compound of Formula (I), and a method of treating or preventing a disease in which BTK plays a role.本發明關於式(I)化合物：或其醫藥上可接受之鹽、互變異構物、前藥、溶劑合物、代謝物、多晶形物、其類似物或衍生物，其調節BTK活性，且關於包含式(I)化合物之醫藥組成物及治療或預防疾病之方法，其中，在該疾病中BTK扮演一角色。