PROBLEM TO BE SOLVED: To provide specific tricyclic compounds that can be useful for inhibiting Raf kinase and for treating disorders mediated by Raf kinase.SOLUTION: A compound is represented by the general formula 1 in the figure. (Q is C or N W is C or N X is CH2 or O Y is NR12, O or S Z is O, S, NR13, CO, SO, SO2 or CR13R14 R1 to R6 are each independently hydrogen, halogen, haloalkyl, alkyl or the like.)SELECTED DRAWING: NoneCOPYRIGHT: (C)2017,JPO&INPIT【課題】Rafキナーゼを阻害するために、およびRafキナーゼが介在する障害を処置するために有用でありうる、特定の三環式化合物の提供。【解決手段】下記一般式1で表される化合物。(QはC又はN;WはC又N;XはCH2又はO;YはNR12、O又はS;ZはO、S、NR13、CO、SO、SO2又はCR13R14;R1~R6は夫夫独立に水素、ハロゲン、ハロアルキル、アルキル等。)【選択図】なし
