Dwayne Thomas Friesen,Bruno Caspar Hancock,Rodney James Ketner,David Keith Lyon,James Alan Shriver Nightingale,Ravi Mysore Shanker
申请号：
US11920473
公开号：
US08828438B2
申请日:
2006.05.22
申请国别(地区):
US
年份:
2014
代理人:
摘要：
A solid amorphous dispersion comprises a cholesteryl ester transfer protein (CETP) inhibitor, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA reductase inhibitor), and a concentration enhancing polymer. At least a major portion of the CETP inhibitor in the dispersion is amorphous. The solid amorphous dispersion provides concentration-enhancement of the CETP inhibitor when administered to an aqueous use environment.
